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[37] However when patients with severe CFS/ME physical therapy must be done incrementally

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The headache phase follows the prodromal or aura stages of a migraine, marked by the activation and sensitization of the trigeminovascular system (TVS) and brainstem, leading to disrupted sensory processing and various neurological symptoms indicative of altered brain excitability (29)

Psychosomatic Medicine 73 :344-349